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Timosaponin AIII

CAS No. 41059-79-4

Timosaponin AIII ( Timosaponin AIII )

产品货号. M18529 CAS No. 41059-79-4

Timosaponin AIII induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM).

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥518 有现货
10MG ¥915 有现货
25MG ¥1936 有现货
50MG ¥2778 有现货
100MG ¥4172 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Timosaponin AIII
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Timosaponin AIII induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM).
  • 产品描述
    Timosaponin AIII induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC50: 2.5 μM, BT474 cells; 6 μM, MDAMB231). The Timosaponin AIII pro-apoptotic response is selective for tumor cells over normal cells but autophagy is induced in both.
  • 同义词
    Timosaponin AIII
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    mTORC1
  • 研究领域
    Others-Field
  • 适应症
    ——

化学信息

  • CAS Number
    41059-79-4
  • 分子量
    740.92
  • 分子式
    C39H64O13
  • 纯度
    98%
  • 溶解度
    ——
  • SMILES
    [C@]12([C@@H]3[C@H](C[C@H]1[C@H]1[C@H](CC2)[C@@]2([C@H](CC1)C[C@H](CC2)O[C@H]1[C@H](O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)[C@H]([C@H]([C@H](O1)CO)O)O)C)O[C@@]1([C@H]3C)CC[C@H](CO1)C)C
  • 化学全称
    [(25S)-5-Spirostan-3-yl]2-O-(-D-glucopyranosyl)--D-galactopyranoside

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Wu ZT, et al. Acta Pharmacol Sin. 2014 Sep;35(9):1188-98.
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